› 2mkz

Solution NMR

solution structure of a protein C-terminal domain

Released:
DOI: 10.2210/pdb2mkz/pdb
PDB entry 2mkz coloured by chain, ensemble of 20 models, front view.
PDB entry 2mkz coloured by chain, ensemble of 20 models, side view.
PDB entry 2mkz coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Mechanism of the Rpn13-induced activation of Uch37.
Jiao L, Ouyang S, Shaw N, Song G, Feng Y, Niu F, Qiu W, Zhu H, Hung LW, Zuo X, Eleonora Shtykova V, Zhu P, Dong YH, Xu R, Liu ZJ
Protein Cell 5 616-30 (2014)
PMID: 24752541

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172449 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Proteasomal ubiquitin receptor ADRM1 Chain: A
Molecule details ›
Chain: A
Length: 141 amino acids
Theoretical weight: 14.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q16186 (Residues: 270-407; Coverage: 34%)
Gene names: ADRM1, GP110
Sequence domains: UCH-binding domain
Structure domains: uronate isomerase, domain 2, chain A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 95%
Refinement method: molecular dynamics, simulated annealing
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Meddling with Fate: The Proteasomal Deubiquitinating Enzymes.
de Poot et al. (2017)
5 more

1 mention without citation

Mechanism of the Rpn13-induced activation of Uch37.
Jiao et al. (2014)