› 2ms8

Solution NMR

Solution NMR structure of MAVS CARD

Released:
DOI: 10.2210/pdb2ms8/pdb
PDB entry 2ms8 coloured by chain, ensemble of 20 models, front view.
PDB entry 2ms8 coloured by chain, ensemble of 20 models, side view.
PDB entry 2ms8 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structure determination of helical filaments by solid-state NMR spectroscopy.
He L, Bardiaux B, Ahmed M, Spehr J, König R, Lünsdorf H, Rand U, Lührs T, Ritter C
Proc Natl Acad Sci U S A 113 E272-81 (2016)
PMID: 26733681

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182260 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitochondrial antiviral-signaling protein Chain: A
Molecule details ›
Chain: A
Length: 102 amino acids
Theoretical weight: 11.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7Z434 (Residues: 1-100; Coverage: 19%)
Gene names: IPS1, KIAA1271, MAVS, VISA
Sequence domains: Caspase recruitment domain
Structure domains: Death Domain, Fas

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 89%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Structural biology of supramolecular assemblies by magic-angle spinning NMR spectroscopy.
Quinn et al. (2017)
2 more

1 mention without citation

Structure determination of helical filaments by solid-state NMR spectroscopy.
He et al. (2016)