› 2mx6

Solution NMR

Complex structure of Dvl PDZ domain with ligand

Released:
DOI: 10.2210/pdb2mx6/pdb
PDB entry 2mx6 coloured by chain, ensemble of 20 models, front view.
PDB entry 2mx6 coloured by chain, ensemble of 20 models, side view.
PDB entry 2mx6 coloured by chain, ensemble of 20 models, top view.
Source organisms:
Entry authors: Zhang X, Zheng JJ

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156297 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Segment polarity protein dishevelled homolog DVL-1 Chain: A
Molecule details ›
Chain: A
Length: 90 amino acids
Theoretical weight: 9.63 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P51141 (Residues: 248-337; Coverage: 13%)
Gene names: Dvl, Dvl1
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
(PHQ)WV peptide Chain: B
Molecule details ›
Chain: B
Length: 3 amino acids
Theoretical weight: 456 Da
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 7%
Refinement method: torsion angle dynamics, simulated annealing
Expression systems:
  • Escherichia coli
  • Not provided

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