› 2n10

Solution NMR

Solution structure of MyUb (1080-1131) of human Myosin VI

Released:
DOI: 10.2210/pdb2n10/pdb
PDB entry 2n10 coloured by chain, ensemble of 20 models, front view.
PDB entry 2n10 coloured by chain, ensemble of 20 models, side view.
PDB entry 2n10 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Myosin VI Contains a Compact Structural Motif that Binds to Ubiquitin Chains.
He F, Wollscheid HP, Nowicka U, Biancospino M, Valentini E, Ehlinger A, Acconcia F, Magistrati E, Polo S, Walters KJ
Cell Rep 14 2683-94 (2016)
PMID: 26971995

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193960 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Unconventional myosin-VI Chain: A
Molecule details ›
Chain: A
Length: 60 amino acids
Theoretical weight: 7.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UM54 (Residues: 1080-1131; Coverage: 4%)
Gene names: KIAA0389, MYO6

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 93%
Refinement method: simulated annealing
Expression system: Escherichia coli

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Citations

1 review citation

Optineurin: A Coordinator of Membrane-Associated Cargo Trafficking and Autophagy.
Ryan et al. (2018)
24 other articles

4 mentions without citation

Myosin VI Contains a Compact Structural Motif that Binds to Ubiquitin Chains.
He et al. (2016)
3 more