2n29

Solution NMR

Solution-state NMR structure of Vpu cytoplasmic domain

Released:
Primary publication:
Structural determination of virus protein U from HIV-1 by NMR in membrane environments.
Biochim Biophys Acta 1848 3007-3018 (2015)
PMID: 26362058

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138835 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein Vpu Chain: A
Molecule details ›
Chain: A
Length: 54 amino acids
Theoretical weight: 6.27 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Escherichia coli
UniProt:
  • Canonical: P05919 (Residues: 29-82; Coverage: 66%)
Gene name: vpu
Sequence domains: Vpu protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 42%
Refinement method: simulated annealing
Expression system: Escherichia coli