› 2n6a

Solution NMR

NMR structure of a human calmodulin/connexin-36 peptide hybrid

Released:
DOI: 10.2210/pdb2n6a/pdb
PDB entry 2n6a coloured by chain, ensemble of 18 models, front view.
PDB entry 2n6a coloured by chain, ensemble of 18 models, side view.
PDB entry 2n6a coloured by chain, ensemble of 18 models, top view.
Source organism: Homo sapiens
Entry author: Donaldson L

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-143907 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calmodulin-1; Gap junction delta-2 protein Chain: A
Molecule details ›
Chain: A
Length: 173 amino acids
Theoretical weight: 19.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DP23 (Residues: 6-147; Coverage: 95%)
  • Canonical: Q9UKL4 (Residues: 276-292; Coverage: 5%)
Gene names: CALM, CALM1, CAM, CAM1, GJA9, GJD2
Sequence domains: EF-hand domain pair

Ligands and Environments

1 bound ligand:
Ligand CA 4 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 72%
Refinement method: simulated annealing
Expression system: Escherichia coli

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