› 2n7i

Solution NMR

NMR structure of the prolactin receptor transmembrane domain

Released:
DOI: 10.2210/pdb2n7i/pdb
PDB entry 2n7i coloured by chain, ensemble of 10 models, front view.
PDB entry 2n7i coloured by chain, ensemble of 10 models, side view.
PDB entry 2n7i coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
A combined computational and structural model of the full-length human prolactin receptor.
Bugge K, Papaleo E, Haxholm GW, Hopper JT, Robinson CV, Olsen JG, Lindorff-Larsen K, Kragelund BB
Nat Commun 7 11578 (2016)
PMID: 27174498

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147736 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Prolactin receptor Chain: A
Molecule details ›
Chain: A
Length: 37 amino acids
Theoretical weight: 3.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P16471 (Residues: 230-264; Coverage: 6%)
Gene name: PRLR

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 94%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

10 review citations

The Growth Hormone Receptor: Mechanism of Receptor Activation, Cell Signaling, and Physiological Aspects.
Dehkhoda et al. (2018)
9 more

4 mentions without citation

A combined computational and structural model of the full-length human prolactin receptor.
Bugge et al. (2016)
3 more