› 2n8z

Solution NMR

Apo form of Calmodulin-Like Domain of Human Non-Muscle alpha-actinin 1

Released:
DOI: 10.2210/pdb2n8z/pdb
PDB entry 2n8z coloured by chain, ensemble of 20 models, front view.
PDB entry 2n8z coloured by chain, ensemble of 20 models, side view.
PDB entry 2n8z coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structure and calcium-binding studies of calmodulin-like domain of human non-muscle α-actinin-1.
Drmota Prebil S, Slapšak U, Pavšič M, Ilc G, Puž V, de Almeida Ribeiro E, Anrather D, Hartl M, Backman L, Plavec J, Lenarčič B, Djinović-Carugo K
Sci Rep 6 27383 (2016)
PMID: 27272015

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146323 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-actinin-1 Chain: A
Molecule details ›
Chain: A
Length: 153 amino acids
Theoretical weight: 16.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P12814 (Residues: 743-892; Coverage: 17%)
Gene name: ACTN1
Sequence domains: Ca2+ insensitive EF hand
Structure domains: EF-hand

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 84%
Refinement method: simulated annealing, water refinement
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Proteins with calmodulin-like domains: structures and functional roles.
Villalobo et al. (2019)
2 more

1 mention without citation

Structure and calcium-binding studies of calmodulin-like domain of human non-muscle α-actinin-1.
Drmota Prebil et al. (2016)