› 2ndk

Solution NMR

20 lowest energy ensemble of dermcidin (DCD1L) NMR structure

Released:
DOI: 10.2210/pdb2ndk/pdb
PDB entry 2ndk coloured by chain, ensemble of 20 models, front view.
PDB entry 2ndk coloured by chain, ensemble of 20 models, side view.
PDB entry 2ndk coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis for the bacterial membrane insertion of dermcidin peptide, DCD-1L.
Nguyen VS, Tan KW, Ramesh K, Chew FT, Mok YK
Sci Rep 7 13923 (2017)
PMID: 29066724

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160538 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DCD-1 Chain: A
Molecule details ›
Chain: A
Length: 48 amino acids
Theoretical weight: 4.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P81605 (Residues: 63-110; Coverage: 53%)
Gene names: AIDD, DCD, DSEP
Sequence domains: Dermcidin, antibiotic peptide

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 61%
Refinement method: distance geometry
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Metal-Peptide Complexes as Promising Antibiotics to Fight Emerging Drug Resistance: New Perspectives in Tuberculosis.
Di Natale et al. (2020)
6 other articles

2 mentions without citation

Structural basis for the bacterial membrane insertion of dermcidin peptide, DCD-1L.
Nguyen et al. (2017)
1 more