› 2nts

X-ray diffraction
2.4Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129499 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
T cell receptor beta constant 1 Chain: P
Molecule details ›
Chain: P
Length: 240 amino acids
Theoretical weight: 27.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01850 (Residues: 1-127; Coverage: 72%)
Gene name: TRBC1
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Enterotoxin Chain: A
Molecule details ›
Chain: A
Length: 217 amino acids
Theoretical weight: 25.08 KDa
Source organism: Staphylococcus aureus subsp. aureus COL
Expression system: Escherichia coli
UniProt:
  • Canonical: O54476 (Residues: 24-239; Coverage: 99%)
Gene names: FAF17_06350, NCTC13131_00757, SAMEA2078260_00586, SAMEA2078588_00034, SAMEA2080344_00276, SAMEA2081063_00276, SAMEA4008575_00276, SAMEA70146418_00656, entK, entk, sek
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9A
Spacegroup: P212121
Unit cell:
a: 38.591Å b: 108.031Å c: 128.743Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.219 0.219 0.24
Expression system: Escherichia coli

Quick links

Citations

13 review citations

Food poisoning and Staphylococcus aureus enterotoxins.
Argudín et al. (2010)
12 more

7 mentions without citation

Manipulation of Innate and Adaptive Immunity by Staphylococcal Superantigens.
Tuffs et al. (2018)
6 more