2nyz

X-ray diffraction
2.6Å resolution

Viral Chemokine Binding Protein M3 From Murine Gammaherpesvirus68 In Complex With The C- Chemokine XCL1

Released:
Primary publication:
Dual GPCR and GAG mimicry by the M3 chemokine decoy receptor.
J Exp Med 204 3157-72 (2007)
PMID: 18070938

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-128793 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
M3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 382 amino acids
Theoretical weight: 41.83 KDa
Source organism: Murid gammaherpesvirus 4
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: O41925 (Residues: 25-406; Coverage: 94%)
Gene names: GAMMAHV.M3, M3
Sequence domains: M3
Structure domains:
Lymphotactin Chains: D, E
Molecule details ›
Chains: D, E
Length: 93 amino acids
Theoretical weight: 10.29 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P47992 (Residues: 22-114; Coverage: 100%)
Gene names: LTN, SCYC1, XCL1
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: I212121
Unit cell:
a: 84.37Å b: 103.19Å c: 290.94Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.219 0.219 0.272
Expression systems:
  • Spodoptera frugiperda
  • Not provided