› 2o96

X-ray diffraction
3Å resolution

Crystal Structure of the Metal-Free Dimeric Human Mov34 MPN domain (residues 1-177)

Released:
DOI: 10.2210/pdb2o96/pdb
PDB entry 2o96 coloured by chain, front view.
PDB entry 2o96 coloured by chain, side view.
PDB entry 2o96 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The crystal structure of the human Mov34 MPN domain reveals a metal-free dimer.
Sanches M, Alves BS, Zanchin NI, Guimarães BG
J Mol Biol 370 846-55 (2007)
PMID: 17559875

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156388 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
26S proteasome non-ATPase regulatory subunit 7 Chains: A, B
Molecule details ›
Chains: A, B
Length: 178 amino acids
Theoretical weight: 20.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P51665 (Residues: 1-177; Coverage: 55%)
Gene names: MOV34L, PSMD7
Sequence domains: JAB1/Mov34/MPN/PAD-1 ubiquitin protease
Structure domains: Cytidine Deaminase, domain 2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LNLS BEAMLINE D03B-MX1
Spacegroup: C2
Unit cell:
a: 114.701Å b: 96.01Å c: 60.982Å
α: 90° β: 122.14° γ: 90°
R-values:
R R work R free
0.206 0.204 0.26
Expression system: Escherichia coli

Quick links

Citations

11 review citations

Structural biology of the proteasome.
Kish-Trier et al. (2013)
10 more