2oei

X-ray diffraction
1.35Å resolution

Crystal structure of human FE65-WW domain in complex with human Mena peptide

Released:
Source organism: Homo sapiens
Primary publication:
Structural basis for polyproline recognition by the FE65 WW domain.
J Mol Biol 372 970-980 (2007)
PMID: 17686488

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-126157 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Amyloid beta precursor protein binding family B member 1 Chain: A
Molecule details ›
Chain: A
Length: 38 amino acids
Theoretical weight: 4.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O00213 (Residues: 253-289; Coverage: 5%)
Gene names: APBB1, FE65, RIR
Sequence domains: WW domain
poly-proline peptide Chain: B
Molecule details ›
Chain: B
Length: 9 amino acids
Theoretical weight: 908 Da
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12B
Spacegroup: P41212
Unit cell:
a: 36.436Å b: 36.436Å c: 78.78Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.194 0.192 0.224
Expression systems:
  • Escherichia coli
  • Not provided