Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Tyrosine-protein kinase HCK and peptide (preferred)
PDBe Complex ID:
PDB-CPX-140248 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Chemical shift assignment:
79%
Refinement method:
Simulated annealing with generalized born solvent model and NMR distance constraints
Expression systems:
- Escherichia coli BL21
- Not provided