Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Tyrosine-protein kinase HCK and peptide (preferred)
PDBe Complex ID:
PDB-CPX-140249 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tyrosine-protein kinase HCK
Molecule details ›
Chain: A
Length: 86 amino acids
Theoretical weight: 9.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: SH3 domain
Structure domains: SH3 Domains
Length: 86 amino acids
Theoretical weight: 9.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
P08631 (Residues: 61-141; Coverage: 15%)
Sequence domains: SH3 domain
Structure domains: SH3 Domains
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Refinement method:
torsion angle dynamics
Expression systems:
- Escherichia coli BL21
- Not provided
