Function and Biology Details
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Mitogen-activated protein (MAP) kinase p38-like
- Protein kinase domain
- Protein kinase, ATP binding site
- Protein kinase-like domain superfamily
- MAP kinase activated protein kinase, C-terminal
- Serine/threonine-protein kinase, active site
- Mitogen-activated protein (MAP) kinase, conserved site
- Mitogen-activated protein kinase 14
Structure domain:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155866 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Mitogen-activated protein kinase 14
Molecule details ›
Chains: A, B
Length: 366 amino acids
Theoretical weight: 42 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Protein kinase domain
Structure domains:
Length: 366 amino acids
Theoretical weight: 42 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
Q16539 (Residues: 2-360; Coverage: 100%)
Sequence domains: Protein kinase domain
Structure domains:
MAP kinase-activated protein kinase 2
Molecule details ›
Chains: C, D
Length: 406 amino acids
Theoretical weight: 46.29 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Protein kinase domain
Structure domains:
Length: 406 amino acids
Theoretical weight: 46.29 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: P49137 (Residues: 1-400; Coverage: 100%)
Sequence domains: Protein kinase domain
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ALS BEAMLINE 5.0.2
Spacegroup:
P41
Expression system: Spodoptera frugiperda
