› 2p0k

X-ray diffraction
1.75Å resolution

Crystal structure of SCMH1

Released:
DOI: 10.2210/pdb2p0k/pdb
PDB entry 2p0k coloured by chain, front view.
PDB entry 2p0k coloured by chain, side view.
PDB entry 2p0k coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Herzanych N, Senisterra G, Liu Y, Crombet L, Loppnau P, Kozieradzki I, Vedadi M, Weigelt J, Sundstrom M, Arrowsmith CH, Edwards AM, Bochkarev A, Min J, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo trimer
Assembly name:
PDBe Complex ID:
PDB-CPX-188518 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Polycomb protein SCMH1 Chain: A
Molecule details ›
Chain: A
Length: 212 amino acids
Theoretical weight: 23.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q96GD3 (Residues: 27-238; Coverage: 32%)
Gene name: SCMH1
Sequence domains: mbt repeat
Structure domains: SH3 type barrels.

Ligands and Environments

2 bound ligands:
Ligand CL 6 x CL
Ligand PO4 2 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P63
Unit cell:
a: 95.735Å b: 95.735Å c: 43.602Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.171 0.169 0.204
Expression system: Escherichia coli BL21(DE3)

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