Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-140137 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Inhibin beta A chain
Molecule details ›
Chains: A, B
Length: 116 amino acids
Theoretical weight: 12.99 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines
Length: 116 amino acids
Theoretical weight: 12.99 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
- Canonical:
P08476 (Residues: 311-426; Coverage: 29%)
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines
Follistatin
Molecule details ›
Chains: C, D
Length: 315 amino acids
Theoretical weight: 34.8 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
Sequence domains:
Length: 315 amino acids
Theoretical weight: 34.8 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
- Canonical: P19883 (Residues: 30-344; Coverage: 100%)
Sequence domains:
- Follistatin, N-terminal
- Follistatin/Osteonectin-like EGF domain
- Kazal-type serine protease inhibitor domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 5ID-B
Spacegroup:
P2221
Expression system: Cricetulus griseus
