› 2p82

X-ray diffraction
2.1Å resolution

Cysteine protease ATG4A

Released:
DOI: 10.2210/pdb2p82/pdb
PDB entry 2p82 coloured by chain, front view.
PDB entry 2p82 coloured by chain, side view.
PDB entry 2p82 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Walker JR, Davis T, Mujib S, Butler-Cole C, Finerty Jr PJ, Weigelt J, Sundstrom M, Arrowsmith CH, Edwards AM, Bochkarev A, Dhe-Paganon S, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186802 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cysteine protease ATG4A Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 355 amino acids
Theoretical weight: 40.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8WYN0 (Residues: 23-359; Coverage: 85%)
Gene names: APG4A, ATG4A, AUTL2
Sequence domains: Peptidase family C54

Ligands and Environments

2 bound ligands:
Ligand EDO 15 x EDO
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P3121
Unit cell:
a: 94.408Å b: 94.408Å c: 337.339Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.177 0.175 0.213
Expression system: Escherichia coli BL21(DE3)

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