› 2pm5

X-ray diffraction
2.4Å resolution

Human alpha-defensin 1 derivative (HNP1)

Released:
DOI: 10.2210/pdb2pm5/pdb
PDB entry 2pm5 coloured by chain, front view.
PDB entry 2pm5 coloured by chain, side view.
PDB entry 2pm5 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Lubkowski J, Pazgier M, Lu W

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-157840 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neutrophil defensin 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 30 amino acids
Theoretical weight: 3.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P59666 (Residues: 66-94; Coverage: 39%)
Gene names: DEF3, DEFA3
Sequence domains: Mammalian defensin

Ligands and Environments

1 bound ligand:
Ligand PO4 1 x PO4
1 modified residue:
Ligand ORN 6 x ORN

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P4222
Unit cell:
a: 57.409Å b: 57.409Å c: 96.967Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.2 0.218
Expression system: Escherichia coli

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