2pnx

X-ray diffraction
1.8Å resolution

The PHD finger of ING4 in complex with an H3K4Me3 histone peptide

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-163171 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Inhibitor of growth protein 4 Chains: A, C
Molecule details ›
Chains: A, C
Length: 55 amino acids
Theoretical weight: 6.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UNL4 (Residues: 194-246; Coverage: 21%)
Gene names: ING4, My036
Structure domains: Zinc/RING finger domain, C3HC4 (zinc finger)
H3K4Me3 peptide Chains: B, D
Molecule details ›
Chains: B, D
Length: 12 amino acids
Theoretical weight: 1.35 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P43
Unit cell:
a: 68.16Å b: 68.16Å c: 27.96Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.199 0.211
Expression systems:
  • Escherichia coli
  • Not provided