› 2ppl

X-ray diffraction
2.2Å resolution

Human Pancreatic lipase-related protein 1

Released:
DOI: 10.2210/pdb2ppl/pdb
PDB entry 2ppl coloured by chain, front view.
PDB entry 2ppl coloured by chain, side view.
PDB entry 2ppl coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Walker JR, Davis T, Seitova A, Butler-Cole C, Weigelt J, Sundstrom M, Arrowsmith CH, Edwards AM, Bochkarev A, Dhe-Paganon S, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed: 
Triacylglycerol + H(2)O = diacylglycerol + a carboxylate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157006 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Inactive pancreatic lipase-related protein 1 Chain: A
Molecule details ›
Chain: A
Length: 485 amino acids
Theoretical weight: 54.03 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P54315 (Residues: 18-467; Coverage: 100%)
Gene names: PLRP1, PNLIPRP1
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand CA 3 x CA
Ligand NA 3 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P41212
Unit cell:
a: 62.871Å b: 62.871Å c: 306.28Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.183 0.18 0.233
Expression system: Spodoptera frugiperda

Quick links