› 2pq3

X-ray diffraction
1.3Å resolution

N-Terminal Calmodulin Zn-Trapped Intermediate

Released:
DOI: 10.2210/pdb2pq3/pdb
PDB entry 2pq3 coloured by chain, front view.
PDB entry 2pq3 coloured by chain, side view.
PDB entry 2pq3 coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
A 1.3-A structure of zinc-bound N-terminal domain of calmodulin elucidates potential early ion-binding step.
Warren JT, Guo Q, Tang WJ
J Mol Biol 374 517-27 (2007)
PMID: 17942116

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-144023 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calmodulin-1 Chain: A
Molecule details ›
Chain: A
Length: 76 amino acids
Theoretical weight: 8.45 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DP29 (Residues: 2-77; Coverage: 51%)
Gene names: CaMI, Calm, Calm1, Cam, Cam1
Sequence domains: EF-hand domain pair

Ligands and Environments

2 bound ligands:
Ligand CAC 1 x CAC
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P43212
Unit cell:
a: 35.211Å b: 35.211Å c: 143.294Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.143 0.143 0.192
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Burns: where has all the calcium (and vitamin D) gone?
Klein GL. (2011)
1 more

6 mentions without citation

Solution NMR structure of the C-terminal EF-hand domain of human cardiac sodium channel NaV1.5.
Chagot et al. (2009)
5 more