Function and Biology Details
Reaction catalysed:
Selective cleavage of Arg-|-Ile bond in factor X to form factor Xa.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140354 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Factor VII light chain
Molecule details ›
Chain: L
Length: 94 amino acids
Theoretical weight: 10.26 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
Sequence domains:
Structure domains: Laminin
Length: 94 amino acids
Theoretical weight: 10.26 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
- Canonical:
P08709 (Residues: 109-202; Coverage: 21%)
Sequence domains:
Structure domains: Laminin
Factor VII heavy chain
Molecule details ›
Chain: H
Length: 254 amino acids
Theoretical weight: 28.1 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Length: 254 amino acids
Theoretical weight: 28.1 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
- Canonical: P08709 (Residues: 213-466; Coverage: 57%)
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Tissue factor
Molecule details ›
Chain: T
Length: 204 amino acids
Theoretical weight: 23.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains: Immunoglobulins
Length: 204 amino acids
Theoretical weight: 23.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P13726 (Residues: 38-241; Coverage: 78%)
Sequence domains:
Structure domains: Immunoglobulins
