› 2q2f

X-ray diffraction
1.5Å resolution

Structure of the human Selenoprotein S (VCP-interacting membrane protein)

Released:
DOI: 10.2210/pdb2q2f/pdb
PDB entry 2q2f coloured by chain, front view.
PDB entry 2q2f coloured by chain, side view.
PDB entry 2q2f coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Walker JR, Paramanathan R, Butler-Cole C, Weigelt J, Sundstrom M, Arrowsmith CH, Edwards AM, Bochkarev A, Dhe-Paganon S, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189670 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Selenoprotein S Chain: A
Molecule details ›
Chain: A
Length: 89 amino acids
Theoretical weight: 10.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9BQE4 (Residues: 52-122; Coverage: 38%)
Gene names: AD-015, SBBI8, SELENOS, SELS, VIMP
Sequence domains: Selenoprotein S (SelS)
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces

Ligands and Environments

2 bound ligands:
Ligand CL 2 x CL
Ligand GOL 1 x GOL
1 modified residue:
Ligand MSE 4 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: C2
Unit cell:
a: 119.666Å b: 18.705Å c: 37.992Å
α: 90° β: 93.36° γ: 90°
R-values:
R R work R free
0.183 0.181 0.214
Expression system: Escherichia coli BL21(DE3)

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