2q5x

X-ray diffraction
1.9Å resolution

Crystal Structure of the C-terminal domain of hNup98

Released:
Source organism: Homo sapiens
Primary publication:
Structural constraints on autoprocessing of the human nucleoporin Nup98.
Protein Sci 17 494-505 (2008)
PMID: 18287282

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-156675 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nuclear pore complex protein Nup98 Chain: A
Molecule details ›
Chain: A
Length: 155 amino acids
Theoretical weight: 17.54 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P52948 (Residues: 733-887; Coverage: 9%)
Gene names: ADAR2, NUP98
Sequence domains: Nucleoporin autopeptidase
Structure domains: Peptidase S59, nucleoporin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P41212
Unit cell:
a: 69.674Å b: 69.674Å c: 90.964Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.206 0.229
Expression system: Escherichia coli BL21(DE3)