› 2q7z

X-ray solution scattering

Solution Structure of the 30 SCR domains of human Complement Receptor 1

Released:
DOI: 10.2210/pdb2q7z/pdb
PDB entry 2q7z coloured by chain, ensemble of 5 models, front view.
PDB entry 2q7z coloured by chain, ensemble of 5 models, side view.
PDB entry 2q7z coloured by chain, ensemble of 5 models, top view.
Source organism: Homo sapiens
Primary publication:
The partly folded back solution structure arrangement of the 30 SCR domains in human complement receptor type 1 (CR1) permits access to its C3b and C4b ligands.
Furtado PB, Huang CY, Ihyembe D, Hammond RA, Marsh HC, Perkins SJ
J Mol Biol 375 102-18 (2008)
PMID: 18028942

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148214 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Complement receptor type 1 Chain: A
Molecule details ›
Chain: A
Length: 1931 amino acids
Theoretical weight: 212.4 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P17927 (Residues: 42-1972; Coverage: 97%)
Gene names: C3BR, CR1
Sequence domains: Sushi repeat (SCR repeat)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Expression system: Cricetulus griseus

Quick links

Citations

5 review citations

The structure, genetic polymorphisms, expression and biological functions of complement receptor type 1 (CR1/CD35).
Liu et al. (2009)
4 more

4 mentions without citation

The apicomplexan glideosome and adhesins - Structures and function.
Boucher et al. (2015)
3 more