2qll

X-ray diffraction
2.56Å resolution

Human liver glycogen phosphorylase- GL complex

Released:

Function and Biology Details

Reaction catalysed:
((1->4)-alpha-D-glucosyl)(n) + phosphate = ((1->4)-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-139194 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Glycogen phosphorylase, liver form Chain: A
Molecule details ›
Chain: A
Length: 847 amino acids
Theoretical weight: 97.36 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
  • Canonical: P06737 (Residues: 1-847; Coverage: 100%)
Gene name: PYGL
Sequence domains: Carbohydrate phosphorylase
Structure domains: Glycogen Phosphorylase B;
protein targeting to glycogen - GL Chain: B
Molecule details ›
Chain: B
Length: 4 amino acids
Theoretical weight: 499 Da
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments


Cofactor: Ligand PLP 1 x PLP
No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P3121
Unit cell:
a: 123.986Å b: 123.986Å c: 125.695Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.206 0.203 0.276
Expression systems:
  • unidentified baculovirus
  • Not provided