› 2qq8

X-ray diffraction
2Å resolution

Crystal structure of the putative RabGAP domain of human TBC1 domain family member 14

Released:
DOI: 10.2210/pdb2qq8/pdb
PDB entry 2qq8 coloured by chain, front view.
PDB entry 2qq8 coloured by chain, side view.
PDB entry 2qq8 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Tong Y, Tempel W, Dimov S, Landry R, Arrowsmith CH, Edwards AM, Sundstrom M, Weigelt J, Bochkarev A, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192843 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TBC1 domain family member 14 Chain: A
Molecule details ›
Chain: A
Length: 334 amino acids
Theoretical weight: 38.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9P2M4 (Residues: 372-687; Coverage: 46%)
Gene names: KIAA1322, TBC1D14
Sequence domains: Rab-GTPase-TBC domain
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand UNX 3 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1, APS BEAMLINE 19-ID
Spacegroup: P43212
Unit cell:
a: 123.52Å b: 123.52Å c: 48.608Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.195 0.235
Expression system: Escherichia coli

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