Function and Biology Details
Reaction catalysed:
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193823 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
DNA (cytosine-5)-methyltransferase 3A
Molecule details ›
Chains: A, D, E, H
Length: 295 amino acids
Theoretical weight: 33.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: C-5 cytosine-specific DNA methylase
Structure domains:
Length: 295 amino acids
Theoretical weight: 33.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q9Y6K1 (Residues: 627-912; Coverage: 31%)
Sequence domains: C-5 cytosine-specific DNA methylase
Structure domains:
DNA (cytosine-5)-methyltransferase 3-like
Molecule details ›
Chains: B, C, F, G
Length: 230 amino acids
Theoretical weight: 26.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Structure domains: Vaccinia Virus protein VP39
Length: 230 amino acids
Theoretical weight: 26.69 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q9UJW3 (Residues: 160-386; Coverage: 59%)
Structure domains: Vaccinia Virus protein VP39
