Function and Biology Details
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132519 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (5 distinct):
Factor VIIIa heavy chain, 92 kDa isoform
Molecule details ›
Chain: A
Length: 742 amino acids
Theoretical weight: 84.95 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
Sequence domains: Multicopper oxidase
Structure domains: Cupredoxins - blue copper proteins
Length: 742 amino acids
Theoretical weight: 84.95 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
- Canonical:
P00451 (Residues: 19-760; Coverage: 32%)
Sequence domains: Multicopper oxidase
Structure domains: Cupredoxins - blue copper proteins
Factor VIIIa light chain
Molecule details ›
Chain: B
Length: 770 amino acids
Theoretical weight: 88.92 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
Sequence domains:
Structure domains:
Length: 770 amino acids
Theoretical weight: 88.92 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
- Canonical: P00451 (Residues: 1582-2351; Coverage: 33%)
Sequence domains:
Structure domains:
Ligands and Environments
No modified residues
Experiments and Validation Details
X-ray source:
ALS BEAMLINE 5.0.2, ALS BEAMLINE 5.0.1
Spacegroup:
P41212
Expression system: Cricetulus griseus
