Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Alpha-1-microglobulin
- Membrane attack complex component/perforin/complement C9
- Membrane attack complex component/perforin (MACPF) domain
- Calycin
- Lipocalin/cytosolic fatty-acid binding domain
- Lipocalin family conserved site
- Complement component C8 gamma chain
- Membrane attack complex component/perforin domain, conserved site
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Complement C8 (preferred)
PDBe Complex ID:
PDB-CPX-139559 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Complement component C8 alpha chain
Molecule details ›
Chain: A
Length: 367 amino acids
Theoretical weight: 41.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: MAC/Perforin domain
Length: 367 amino acids
Theoretical weight: 41.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P07357 (Residues: 133-492; Coverage: 64%)
Sequence domains: MAC/Perforin domain
Complement component C8 gamma chain
Molecule details ›
Chain: C
Length: 184 amino acids
Theoretical weight: 20.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin
Length: 184 amino acids
Theoretical weight: 20.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P07360 (Residues: 21-202; Coverage: 100%)
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin
