› 2rey

X-ray diffraction
1.55Å resolution

Crystal structure of the PDZ domain of human dishevelled 2 (homologous to Drosophila dsh)

Released:
DOI: 10.2210/pdb2rey/pdb
PDB entry 2rey coloured by chain, front view.
PDB entry 2rey coloured by chain, side view.
PDB entry 2rey coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Papagrigoriou E, Gileadi C, Elkins J, Cooper C, Ugochukwu E, Turnbull A, Pike ACW, Gileadi O, von Delft F, Sundstrom M, Arrowsmith CH, Weigelt J, Edwards AM, Doyle D, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127034 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Segment polarity protein dishevelled homolog DVL-2 Chain: A
Molecule details ›
Chain: A
Length: 100 amino acids
Theoretical weight: 10.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O14641 (Residues: 261-355; Coverage: 13%)
Gene name: DVL2
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P6122
Unit cell:
a: 69.644Å b: 69.644Å c: 57.54Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.212 0.211 0.24
Expression system: Escherichia coli

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