› 2rmz

Solution NMR

Bicelle-embedded integrin beta3 transmembrane segment

Released:
DOI: 10.2210/pdb2rmz/pdb
PDB entry 2rmz coloured by chain, ensemble of 21 models, front view.
PDB entry 2rmz coloured by chain, ensemble of 21 models, side view.
PDB entry 2rmz coloured by chain, ensemble of 21 models, top view.
Source organism: Homo sapiens
Primary publication:
Structure of the integrin beta3 transmembrane segment in phospholipid bicelles and detergent micelles.
Lau TL, Partridge AW, Ginsberg MH, Ulmer TS
Biochemistry 47 4008-16 (2008)
PMID: 18321071

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138433 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Integrin beta-3 Chain: A
Molecule details ›
Chain: A
Length: 43 amino acids
Theoretical weight: 4.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05106 (Residues: 712-753; Coverage: 6%)
Gene names: GP3A, ITGB3
Structure domains: Cytochrome c1, transmembrane anchor, C-terminal

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

24 review citations

The final steps of integrin activation: the end game.
Shattil et al. (2010)
23 more

6 mentions without citation

The tail of integrin activation.
Anthis et al. (2011)
5 more