Function and Biology Details
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139751 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Epidermal growth factor receptor kinase substrate 8-like protein 1
Molecule details ›
Chain: A
Length: 64 amino acids
Theoretical weight: 7.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: SH3 domain
Structure domains: SH3 Domains
Length: 64 amino acids
Theoretical weight: 7.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q8TE68 (Residues: 478-537; Coverage: 8%)
Sequence domains: SH3 domain
Structure domains: SH3 Domains
T-cell surface glycoprotein CD3 epsilon chain
Molecule details ›
Chain: B
Length: 12 amino acids
Theoretical weight: 1.39 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Sequence domains: Immunoreceptor tyrosine-based activation motif
Length: 12 amino acids
Theoretical weight: 1.39 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P07766 (Residues: 181-192; Coverage: 7%)
Sequence domains: Immunoreceptor tyrosine-based activation motif
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Chemical shift assignment:
84%
Refinement method:
torsion angle dynamics
Expression systems:
- Escherichia coli
- Not provided
