› 2rrb

Solution NMR

Refinement of RNA binding domain in human Tra2 beta protein

Released:
DOI: 10.2210/pdb2rrb/pdb
PDB entry 2rrb coloured by chain, ensemble of 20 models, front view.
PDB entry 2rrb coloured by chain, ensemble of 20 models, side view.
PDB entry 2rrb coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis for the dual RNA-recognition modes of human Tra2-β RRM.
Tsuda K, Someya T, Kuwasako K, Takahashi M, He F, Unzai S, Inoue M, Harada T, Watanabe S, Terada T, Kobayashi N, Shirouzu M, Kigawa T, Tanaka A, Sugano S, Güntert P, Yokoyama S, Muto Y
Nucleic Acids Res 39 1538-53 (2011)
PMID: 20926394

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158891 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transformer-2 protein homolog beta Chain: A
Molecule details ›
Chain: A
Length: 96 amino acids
Theoretical weight: 10.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P62995 (Residues: 111-201; Coverage: 32%)
Gene names: SFRS10, TRA2B
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DGSA-distance geometry simulated annealing
Expression system: Escherichia coli

Quick links

Citations

7 review citations

RRM-RNA recognition: NMR or crystallography…and new findings.
Daubner et al. (2013)
6 more

4 mentions without citation

Structural basis for the dual RNA-recognition modes of human Tra2-β RRM.
Tsuda et al. (2011)
3 more