› 2spc

X-ray diffraction
1.8Å resolution

CRYSTAL STRUCTURE OF THE REPETITIVE SEGMENTS OF SPECTRIN

Released:
DOI: 10.2210/pdb2spc/pdb
PDB entry 2spc coloured by chain, front view.
PDB entry 2spc coloured by chain, side view.
PDB entry 2spc coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Crystal structure of the repetitive segments of spectrin.
Yan Y, Winograd E, Viel A, Cronin T, Harrison SC, Branton D
Science 262 2027-30 (1993)
PMID: 8266097

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146562 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Spectrin alpha chain Chains: A, B
Molecule details ›
Chains: A, B
Length: 107 amino acids
Theoretical weight: 12.29 KDa
Source organism: Drosophila melanogaster
Expression system: Not provided
UniProt:
  • Canonical: P13395 (Residues: 1391-1497; Coverage: 4%)
Gene names: CG1977, SPEC-A, alpha-Spec
Sequence domains: Spectrin repeat
Structure domains: Methane Monooxygenase Hydroxylase; Chain G, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21212
Unit cell:
a: 46.8Å b: 47.22Å c: 104.43Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.203 0.203 not available
Expression system: Not provided

Quick links

Citations

40 review citations

Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissues.
Bennett et al. (2001)
39 more

12 mentions without citation

Nuclear alpha spectrin: Critical roles in DNA interstrand cross-link repair and genomic stability.
Lambert MW. (2016)
11 more