Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140187 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Internalin B
Molecule details ›
Chains: A, C
Length: 289 amino acids
Theoretical weight: 32.24 KDa
Source organism: Listeria monocytogenes EGD-e
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Structure domains:
Length: 289 amino acids
Theoretical weight: 32.24 KDa
Source organism: Listeria monocytogenes EGD-e
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P0DQD2 (Residues: 36-321; Coverage: 48%)
Sequence domains:
Structure domains:
Hepatocyte growth factor receptor
Molecule details ›
Chains: B, D
Length: 727 amino acids
Theoretical weight: 81.9 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
Sequence domains:
Structure domains:
Length: 727 amino acids
Theoretical weight: 81.9 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
- Canonical: P08581 (Residues: 25-741; Coverage: 53%)
Sequence domains:
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID23-2
Spacegroup:
P212121
Expression systems:
- Escherichia coli BL21(DE3)
- Cricetulus griseus
