Function and Biology Details
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
DNA polymerase epsilon subunit 2 (preferred)
PDBe Complex ID:
PDB-CPX-157459 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA polymerase epsilon subunit 2
Molecule details ›
Chain: M
Length: 99 amino acids
Theoretical weight: 11.09 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: DNA polymerases epsilon N terminal
Structure domains: Helicase, Ruva Protein; domain 3
Length: 99 amino acids
Theoretical weight: 11.09 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P56282 (Residues: 1-75; Coverage: 14%)
Sequence domains: DNA polymerases epsilon N terminal
Structure domains: Helicase, Ruva Protein; domain 3
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Chemical shift assignment:
94%
Refinement method:
simulated annealing
Expression system: Escherichia coli BL21(DE3)
