2v76

X-ray diffraction
1.6Å resolution

Crystal structure of the human dok1 PTB domain

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189248 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Docking protein 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 107 amino acids
Theoretical weight: 12.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q99704 (Residues: 152-256; Coverage: 22%)
Gene name: DOK1
Sequence domains: PTB domain (IRS-1 type)
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: C2
Unit cell:
a: 76.88Å b: 100.168Å c: 67.101Å
α: 90° β: 117.34° γ: 90°
R-values:
R R work R free
0.19 0.188 0.224
Expression system: Escherichia coli