2v8s

X-ray diffraction
2.22Å resolution

VTI1B HABC DOMAIN - EPSINR ENTH DOMAIN COMPLEX

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-172079 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Clathrin interactor 1 Chain: E
Molecule details ›
Chain: E
Length: 147 amino acids
Theoretical weight: 17.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q14677 (Residues: 20-166; Coverage: 24%)
Gene names: CLINT1, ENTH, EPN4, EPNR, KIAA0171
Sequence domains: ENTH domain
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
Vesicle transport through interaction with t-SNAREs homolog 1B Chain: V
Molecule details ›
Chain: V
Length: 96 amino acids
Theoretical weight: 11.25 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9UEU0 (Residues: 1-96; Coverage: 41%)
Gene names: VTI1, VTI1B, VTI1L, VTI1L1, VTI2
Sequence domains: Vesicle transport v-SNARE protein N-terminus
Structure domains: t-snare proteins

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2
Unit cell:
a: 102.231Å b: 60.935Å c: 40.998Å
α: 90° β: 94.09° γ: 90°
R-values:
R R work R free
0.201 0.196 0.284
Expression system: Escherichia coli BL21(DE3)