› 2v9q

X-ray diffraction
2.5Å resolution

First and second Ig domains from human Robo1

Released:
DOI: 10.2210/pdb2v9q/pdb
PDB entry 2v9q coloured by chain, front view.
PDB entry 2v9q coloured by chain, side view.
PDB entry 2v9q coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural insights into the Slit-Robo complex.
Morlot C, Thielens NM, Ravelli RB, Hemrika W, Romijn RA, Gros P, Cusack S, McCarthy AA
Proc Natl Acad Sci U S A 104 14923-8 (2007)
PMID: 17848514

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195377 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Roundabout homolog 1 Chain: A
Molecule details ›
Chain: A
Length: 212 amino acids
Theoretical weight: 23.59 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9Y6N7 (Residues: 58-266; Coverage: 13%)
Gene names: DUTT1, ROBO1
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand HG 2 x HG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P21212
Unit cell:
a: 38.23Å b: 68.53Å c: 103.88Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.229 0.227 0.28
Expression system: Homo sapiens

Quick links

Citations

28 review citations

Axon guidance molecules in vascular patterning.
Adams et al. (2010)
27 more

4 mentions without citation

Structural insights into the Slit-Robo complex.
Morlot et al. (2007)
3 more