› 2vt8

X-ray diffraction
2.6Å resolution

Structure of a conserved dimerisation domain within Fbox7 and PI31

Released:
DOI: 10.2210/pdb2vt8/pdb
PDB entry 2vt8 coloured by chain, front view.
PDB entry 2vt8 coloured by chain, side view.
PDB entry 2vt8 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of a conserved dimerization domain within the F-box protein Fbxo7 and the PI31 proteasome inhibitor.
Kirk R, Laman H, Knowles PP, Murray-Rust J, Lomonosov M, Meziane el K, McDonald NQ
J Biol Chem 283 22325-35 (2008)
PMID: 18495667

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187675 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Proteasome inhibitor PI31 subunit Chains: A, B
Molecule details ›
Chains: A, B
Length: 153 amino acids
Theoretical weight: 17.2 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q92530 (Residues: 1-151; Coverage: 56%)
Gene name: PSMF1
Sequence domains: PI31 proteasome regulator N-terminal
Structure domains: Protein Transport Mog1p; Chain A

Ligands and Environments

No bound ligands
1 modified residue:
Ligand CSO 4 x CSO

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: C2
Unit cell:
a: 109.498Å b: 45.212Å c: 67.279Å
α: 90° β: 111.54° γ: 90°
R-values:
R R work R free
0.206 0.203 0.256
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

10 review citations

The proteasome: overview of structure and functions.
Tanaka K. (2009)
9 more

2 mentions without citation

Structure of Spo0M, a sporulation-control protein from Bacillus subtilis.
Sonoda et al. (2015)
1 more