› 2w4f

X-ray diffraction
1.3Å resolution

CRYSTAL STRUCTURE OF THE FIRST PDZ DOMAIN OF HUMAN SCRIB1

Released:
DOI: 10.2210/pdb2w4f/pdb
PDB entry 2w4f coloured by chain, front view.
PDB entry 2w4f coloured by chain, side view.
PDB entry 2w4f coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Hozjan V, Pilka ES, Roos AK, W Yue W, Phillips C, Bray J, Cooper C, Salah E, Elkins JM, Muniz JRC, Arrowsmith CH, Weigelt J, Edwards AM, von Delft F, Bountra C, Doyle DA, Oppermann U

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171945 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein scribble homolog Chain: A
Molecule details ›
Chain: A
Length: 97 amino acids
Theoretical weight: 10.22 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q14160 (Residues: 725-815; Coverage: 6%)
Gene names: CRIB1, KIAA0147, LAP4, SCRB1, SCRIB, VARTUL
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

1 bound ligand:
Ligand EDO 3 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P212121
Unit cell:
a: 38.216Å b: 41.829Å c: 49.897Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.175 0.173 0.221
Expression system: Escherichia coli BL21(DE3)

Quick links