Function and Biology Details
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Complement factor H and Factor H binding protein (preferred)
PDBe Complex ID:
PDB-CPX-140218 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Complement factor H
Molecule details ›
Chains: A, B, E, G
Length: 123 amino acids
Theoretical weight: 14.22 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Sushi repeat (SCR repeat)
Structure domains: Complement Module, domain 1
Length: 123 amino acids
Theoretical weight: 14.22 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P08603 (Residues: 321-443; Coverage: 10%)
Sequence domains: Sushi repeat (SCR repeat)
Structure domains: Complement Module, domain 1
Factor H binding protein
Molecule details ›
Chains: C, D, F, H
Length: 253 amino acids
Theoretical weight: 26.98 KDa
Source organism: Neisseria meningitidis
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Structure domains:
Length: 253 amino acids
Theoretical weight: 26.98 KDa
Source organism: Neisseria meningitidis
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: Q9JXV4 (Residues: 25-274; Coverage: 98%)
Sequence domains:
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID14-4
Spacegroup:
P1
Expression system: Escherichia coli BL21(DE3)
