Function and Biology Details
Biochemical function:
- not assigned
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-208756 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (5 distinct):
HLA class II histocompatibility antigen, DR alpha chain
Molecule details ›
Chains: A, E
Length: 194 amino acids
Theoretical weight: 22.44 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
Sequence domains:
Structure domains:
Length: 194 amino acids
Theoretical weight: 22.44 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
- Canonical:
P01903 (Residues: 26-218; Coverage: 84%)
Sequence domains:
Structure domains:
HLA class II histocompatibility antigen, DRB1 beta chain
Molecule details ›
Chains: B, F
Length: 200 amino acids
Theoretical weight: 23.21 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
Sequence domains:
Structure domains:
Length: 200 amino acids
Theoretical weight: 23.21 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
- Canonical: P01911 (Residues: 30-228; Coverage: 84%)
Sequence domains:
Structure domains:
Ligands and Environments
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID23-2
Spacegroup:
P212121
Expression systems:
- Drosophila melanogaster
- Escherichia coli BL21(DE3)
