Function and Biology Details
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assemblies composition:
Assembly name:
Complement C3b complex and Complement factor H (preferred)
PDBe Complex ID:
PDB-CPX-133828 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Complement C3 beta chain
Molecule details ›
Chain: A
Length: 645 amino acids
Theoretical weight: 71.39 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 645 amino acids
Theoretical weight: 71.39 KDa
Source organism: Homo sapiens
UniProt:
- Canonical:
P01024 (Residues: 23-667; Coverage: 39%)
Sequence domains:
- Macroglobulin domain MG1
- MG2 domain
- Macroglobulin domain MG3
- Macroglobulin domain MG4
- Alpha-2-macroglobulin bait region domain
Complement C3b alpha' chain
Molecule details ›
Chain: B
Length: 915 amino acids
Theoretical weight: 104.07 KDa
Source organism: Homo sapiens
UniProt:
Sequence domains:
Length: 915 amino acids
Theoretical weight: 104.07 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P01024 (Residues: 749-1663; Coverage: 56%)
Sequence domains:
- Alpha-2-macroglobulin family
- Complement component 3, CUB domain 1
- A-macroglobulin TED domain
- Complement component 3, CUB domain 2
- A-macroglobulin receptor binding domain
- UNC-6/NTR/C345C module
Complement factor H
Molecule details ›
Chain: C
Length: 277 amino acids
Theoretical weight: 31.22 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Sushi repeat (SCR repeat)
Structure domains: Complement Module, domain 1
Length: 277 amino acids
Theoretical weight: 31.22 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P08603 (Residues: 18-264; Coverage: 20%)
Sequence domains: Sushi repeat (SCR repeat)
Structure domains: Complement Module, domain 1
