2wuh

X-ray diffraction
1.6Å resolution

Crystal structure of the DDR2 discoidin domain bound to a triple- helical collagen peptide

Released:

Function and Biology Details

Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-163301 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Discoidin domain-containing receptor 2 Chain: A
Molecule details ›
Chain: A
Length: 178 amino acids
Theoretical weight: 20.11 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q16832 (Residues: 22-190; Coverage: 20%)
Gene names: DDR2, NTRKR3, TKT, TYRO10
Sequence domains: F5/8 type C domain
Structure domains: Galactose-binding domain-like
COLLAGEN PEPTIDE Chains: B, C, D
Molecule details ›
Chains: B, C, D
Length: 29 amino acids
Theoretical weight: 2.63 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands
2 modified residues:

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P1
Unit cell:
a: 33.397Å b: 40.863Å c: 48.917Å
α: 66.19° β: 88.9° γ: 76.92°
R-values:
R R work R free
0.202 0.202 0.23
Expression systems:
  • Homo sapiens
  • Not provided