› 2wz9

X-ray diffraction
1.55Å resolution

Crystal structure of the thioredoxin domain of human TXNL2

Released:
DOI: 10.2210/pdb2wz9/pdb
PDB entry 2wz9 coloured by chain, front view.
PDB entry 2wz9 coloured by chain, side view.
PDB entry 2wz9 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Vollmar M, Johannson C, Cocking R, Pike ACW, Muniz JRC, Edwards A, von Delft F, Bountra C, Arrowsmith CH, Weigelt J, Kavanagh KL

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131188 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutaredoxin-3 Chain: A
Molecule details ›
Chain: A
Length: 153 amino acids
Theoretical weight: 16.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O76003 (Residues: 1-134; Coverage: 40%)
Gene names: GLRX3, HUSSY-22, PICOT, TXNL2
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P212121
Unit cell:
a: 42.63Å b: 52.06Å c: 58.6Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.156 0.154 0.179
Expression system: Escherichia coli BL21(DE3)

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