› 2xo3

X-ray diffraction
2.3Å resolution

Human Annexin V with incorporated Methionine analogue Homopropargylglycine

Released:
DOI: 10.2210/pdb2xo3/pdb
PDB entry 2xo3 coloured by chain, front view.
PDB entry 2xo3 coloured by chain, side view.
PDB entry 2xo3 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Debela M, Merkel L, Goettig P, Budisa N

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140372 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Annexin A5 Chain: A
Molecule details ›
Chain: A
Length: 320 amino acids
Theoretical weight: 35.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P08758 (Residues: 1-320; Coverage: 100%)
Gene names: ANX5, ANXA5, ENX2, PP4
Sequence domains: Annexin
Structure domains: Annexin

Ligands and Environments

2 bound ligands:
Ligand CA 2 x CA
Ligand SO4 2 x SO4
1 modified residue:
Ligand IZO 8 x IZO

Experiments and Validation Details

Entry percentile scores
X-ray source: MPG/DESY, HAMBURG BEAMLINE BW6
Spacegroup: R3
Unit cell:
a: 154.965Å b: 154.965Å c: 35.58Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.262 0.262 0.291
Expression system: Escherichia coli

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